The brand name for this drug combination is Vytorin. tender, swollen glands in neck. What Are the Injectable Alternatives to Statins? dark colored urine. Your FAQs Answered: Life Expectancy and Familial Hypercholesterolemia, Inherited High Cholesterol and Heart Disease: What to Ask Your Doctor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Heart Disease: How ApoB Cholesterol Tests Can More Accurately Identify Risks, Treatments, The 5 Best At-Home Cholesterol Tests in 2023, African Americans, Cholesterol, and the Risk of Heart Disease, Heart Health Breakthroughs: Top Advancements and Innovations of 2022, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, what dose of drug you were taking when you had the side effect, how soon after starting that dose you had the side effect, what your symptoms were from the side effect, what other medications you were also taking, any other information you feel is important, taking other medications, especially high dose statin drugs. Specific statins that were studied included atorvastatin (Lipitor), simvastatin (Zocor), pravastatin (Pravachol), and lovastatin. If you develop increased liver enzyme levels, your doctor may make changes to your treatment plan. Depending on your age or other medical conditions you may have, you may be at higher risk of developing rhabdomyolysis while taking Zetia. Would a lower dose of Zetia help to reduce my risk of side effects? Lying down on the bed, and raising your legs. LDL cholesterol was reduced by 15% more in children who took Zetia and simvastatin than in children who took simvastatin alone. Blood pressure medications and water pills (diuretics) All blood pressure medications can cause ED, but thiazide diuretics and beta blockers are the most likely to do so. Primary hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Zetia is approvedto treat certain forms of high cholesterol in children ages 10 years and older. Energy Drinks, such as Red Bull, should be avoided in those with POTS. Sharing this information can help you avoid potential interactions. Over time, plant sterols can build up in your blood vessels and raise your risk of heart disease. Note: Some of the drugs listed here are used off-label to treat these specific conditions. POTS is an unusual condition in which your heart rate speeds up by 30 or more beats per minute with little or no change in blood pressure. Tell them about all prescription, over-the-counter, and other drugs you take. It wasnt reported during studies of the drug. However, 0.3% of people who took Zetia alone experienced joint pain so bothersome that they had to stop treatment. Then you can share this information with your doctor. Learn about the side effects it can cause and how to manage them. For most people, CoQ10 isnt a harmful or dangerous supplement. An allergic reaction is possible after using Zetia. Clinical studies looked at Zetia for the treatment of primary hyperlipidemia in adults and in children ages 10 years and older. Zetia shouldnt cause weight gain or weight loss. They may suggest foods that can help lower your cholesterol and reduce your risk of weight gain. Taking Zetia with a statin may cause this side effect. Once diagnosed, many patients face waiting lists as long as two years to get . For this purpose, Zetia may be used: The only FDA-approved dosage of Zetia is 10 mg once a day. Absorption isnt affected by food. More common side effects in people taking Zetia* include: * In studies, these side effects were reported in people who took Zetia by itself. * Sex and gender exist on spectrums. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Other drugs are available that can treat your conditions. POTS affects the body's ability to pump blood from the legs to the rest of the body while standing. Zetia is contraindicated under the following conditions: Zetia tablets should be stored at a room temperature of 77F (25C) in a tightly sealed container away from light. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. They may be able to help determine whats causing your hair loss. The bottom line: Zetia may cause fewer side effects than statins (though some clinicians might dispute that) but Zetia may cause muscle problems and other adverse reactions. POTS-related fatigue is physical in nature . There arent any herbs or supplements that have been specifically reported to interact with Zetia. The effect of Zetia, atorvastatin, or simvastatin on other types of cholesterol levels in this study isnt known. If youre interested in finding an alternative to Zetia, talk with your doctor. If you no longer need to take Zetia and have leftover medication, its important to dispose of it safely. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. For this purpose, Zetia is used with a low-cholesterol diet (but with no other drugs) in adults and in children ages 10 years and older. Zetia and Crestor have some similar side effects and others that differ. Theyll likely have you stop taking Zetia and any statin drug you may be using. Zetia is indicated as an adjunct to a low-cholesterol diet for treatment of the following types of hyperlipidemia: For treatment of primary hyperlipidemia, Zetia is indicated to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (non-HDL) cholesterol, and apiloprotein B (ApoB). (A class of drugs is a group of medications that work in a similar way.) Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. This helps prevent others, including children and pets, from taking the drug by accident. Zetia is FDA-approved to treat certain forms of high cholesterol in adults and children. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. (A class of drugs is a group of medications that work in a similar way.) Diarrhea is a common side effect of Zetia. Its not known if Zetia is safe to take during pregnancy. Drugs in this class prevent your small intestine from absorbing cholesterol. Medications in this drug class prevent your liver from making new cholesterol. All rights reserved. Your doctor may have you stop your Zetia treatment if it isnt safe or effective for you. Read more about these alternatives to traditional statin, Having high cholesterol puts you at risk for a heart attack or stroke. stomach pain. Many rare diseases have limited information. In order to diagnose POTS, your doctor will need to measure your heart rate when you are sitting at rest. In these groups, joint pain occurred in: The length of time that adults and children experienced joint pain while taking Zetia in these clinical studies isnt known. They may want to select a different treatment option for you. Learn about the drugs dosages, forms, strengths, and more. Side effects could occur in children who are breastfed by someone taking a statin drug. If you have joint pain while taking Zetia, you may also experience swelling, redness, or weakness in your joints. Stopping Zetia treatment shouldnt cause any noticeable side effects. upper respiratory tract infection, including the common cold. pain in your arms or legs. Watch Part 2 here: https://youtu.be/HPfo2QOa89YHello Friends! If your doctor has prescribed Zetia and youre interested in using ezetimibe instead, talk with your doctor. This can cause gallstones (hardened stones in your gallbladder). Zetia generally costs more than Crestor. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. Cardiology 33 years experience. The list below includes factors to consider. Some people experience mild side effects with Zetia. Zetia may cause joint pain. Uses. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. It is created by eHealthMe based on reports of 45,364 people who have side effects when taking Zetia from the FDA, and is updated regularly. Here are answers to some frequently asked questions about Zetia. . Typical symptoms of POTS include: heart palpitations (feeling your heart beating or racing) dizziness or lightheadedness. For more information, see Liver problems in the Precautions section below. A generic drug is an exact copy of the active drug in a brand-name medication. However, its important that you dont stop taking Zetia without first talking with your doctor. Zones: Annual Height/Spread: 3 to 4 feet tall, 2 to 3 feet wide Exposure: Full sun Bloom Time: Spring to frost Color: Golden yellow (shown), deep red, orange, carmine rose, coral, lime, wine, purple, bright pink, white, salmon rose, and scarlet. Youll also need to check your insurance plan, as it may only cover one or the other. Sometimes brain zaps are also accompanied by dizziness, pain, or tinnitus, a ringing in the ears. In these studies, 12 weeks of treatment with Zetia and fenofibrate was compared with Zetia taken alone, fenofibrate taken alone, or a placebo (a treatment with no active drug). People with this condition have high levels of LDL (bad) cholesterol. Hot and cold spells. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. Its not known how many adults and children experienced muscle pain in clinical studies of other conditions treated with Zetia and statin drugs. Cholestyramine (Prevalite) is a drug used to treat high cholesterol. Yes, treatment with Zetia should lower your triglycerides. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. Below are examples of these side effects. You may also be having a reaction to all the medications mixed together. If your muscle-related side effects dont go away or become severe, tell your doctor right away. Its also not known if the drug is safe to take while breastfeeding or whether the drug passes into breast milk. If you and your doctor determine that Zetia is safe and effective for you, youll likely take it long term. Before trying something new, its common to look for written reviews about the experiences of others. Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health . (For information on side effects, see the Zetia side effects section above.). Treatment is targeted at relieving low blood volume or regulating circulatory problems that may cause the disorder. Its primary metabolic pathway is via hepatic glucuronic conjunction. People with this condition have high levels of plant sterols. The following information describes dosages that are commonly used or recommended. Statins shouldnt be used during pregnancy. Less commonly, taking Zetia may lead to serious side effects. Phase IV trials are used to detect adverse drug . Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. See the Zetia prescribing information for details. Yes, there are a few. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. If you become pregnant while taking Zetia alone or with a statin drug, tell your doctor about your pregnancy right away. Zetia contains the active drug ezetimibe. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. You can take Zetia with or without food. It can also interact with certain supplements as well as certain foods. Talk with your doctor if you experience diarrhea while taking this medication. The expiration date helps guarantee that the medication is effective during this time. Get emergency medical help if you have signs of an allergic reaction to Zetia: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Clinical studies involved adults and children ages 10 years and older. Instead, it belongs to a class of drugs called cholesterol absorption inhibitors. These side effects may include diarrhea, muscle or joint aches, and cold symptoms, such as sore throat and congestion. Some people have mild symptoms, while for others it can have a big impact on their everyday lives. Twelve weeks of treatment with Zetia and atorvastatin or simvastatin was compared with atorvastatin or simvastatin used alone. Zetia is primarily cleared from the body through fecal excretion. Liver problems. The most common side effects of Zetia include: muscle or joint pain, Youll likely take Zetia once a day. Dizziness is a rare side effect of taking Zetia. Reverso Context ofer traducere n context din englez n romn pentru "but as in", cu exemple: Belgium overall has a good track record of achieving the nominal budgetary targets, but as in recent years a strict monitoring will be necessary to achieve the target for 2007. Zetia is meant to be used as a long-term treatment. However, be sure to take the dosage your doctor prescribes for you. * For more information about this side effect, see " Zetia: Side effects explained " below. More research is needed to know for sure. Heres some detail on certain side effects this drug may or may not cause. It isnt known how long adults and children experienced diarrhea while taking Zetia in these clinical studies. However, excessive alcohol use can damage your liver over time. Some may be a better fit for you than others. Zetias mechanism of action is considered complementary to that of statins and fenofibrate. This is especially helpful to do when you first start taking new drugs or using a combination of treatments. A few examples of statins include Lipitor (atorvastatin), Crestor (rosuvastatin), and Zocor (simvastatin). However, several medicines can be prescribed off-label when needed. Use these discussion points about familial hypercholesterolemia to prepare for your doctors appointment. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. This can increase your risk of side effects from either medication. In most cases, these side effects should be temporary. OI is a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. 2. They can suggest ways to help relieve this side effect. Some people witness mild symptoms, some have a big impact on their lives due . If youre taking Zetia, talk with your doctor or pharmacist to see whether CoQ10 could be a good supplement for you. However, animal studies dont always predict what will happen in humans. Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. 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