Events near you Scientists from Cardiff University have uncovered a protein which drives aggressive breast cancer and could be targeted for developing new and improved therapies. Breast Cancer Now is a company limited by guarantee registered in England (9347608) and a charity registered in England and Wales (1160558), Scotland (SC045584) and Isle of Man (1200). Breast Cancer Now is a company limited by guarantee registered in England (9347608) and a charity registered in England and Wales (1160558), Scotland (SC045584) and Isle of Man (1200). We could target LYN to improve therapy options for aggressive breast cancer.”, Professor, Director European Cancer Stem Cell Research Institute (ECSCRI), Copyright Cardiff University. Scientists from Cardiff University have uncovered a protein which drives aggressive breast cancer and could be targeted for developing new and improved therapies. This is in light of current government advice on social contact. To hear from us, enter your email address below. Breast Cancer Now has a Welsh office in Cardiff. Breast Cancer Now is a company limited by guarantee registered in England (9347608) and a charity registered in England and Wales (1160558), Scotland (SC045584) and Isle of Man (1200). Breast Cancer Now is a company limited by guarantee registered in England (9347608) and a charity registered in England and Wales (1160558), Scotland (SC045584) and Isle of Man (1200). The European Cancer Stem Cell Research Institute, based with Cardiff University, has repurposed a current cancer therapy, TRAIL, to find a new treatment for advanced cancers that are resistant to anti-hormone therapy. Breastfriends is a friendly, informal support group for anyone who has had a diagnosis of breast cancer, whether it was last week, last month, last year or many years ago. Use our location finder and find out what support and fundraising events are in and around Wales. We provide support services all over the country, and work with our volunteers and fundraisers locally. of our undergraduates enter employment or further study shortly after graduating, invested in our biggest campus upgrade for a generation. We run face-to-face support services all over Wales, making sure that everyone gets the support they need. We’d love to keep in touch about news, events and how you can get involved. Use our location finder and find out what support and fundraising events are in and around Wales. Professor Matt Smalley added: "Thanks to Breast Cancer Now, who funded this research, we now understand the role LYN has in aggressive forms of cancer. Professor Matt Smalley, from Cardiff University’s European Cancer Stem Cell Research Institute, said: “There are 150 new cases of breast cancer diagnosed in the UK every day. Important information regarding coronavirus: With regret, we have decided to cancel our, Welcome to Breastfriends Cardiff and Vale. To achieve better outcomes for people facing this disease, we need to better understand how it develops so we can improve therapies. For more information, email us at: info@breastfriendscandv.org.uk, For help and support, visit: Breast Cancer Now, Advice on coronavirus for people with cancer. Registered Office: Fifth Floor, Ibex House, 42-47 Minories, London EC3N 1DY. “We wanted to understand what drives an aggressive type of breast cancer called triple negative, which is resistant to hormone therapy and occurs in around fifteen percent of breast cancer cases. You can help us by volunteering at an event, supporting others, raising awareness or raising money in your area. Interfering with LYN function under experimental conditions killed these BRCA1-mutant cells. Due to the coronavirus (COVID-19) outbreak, from Monday 6 April the majority of our staff will be out of the office. ... Cardiff CF11 9LJ. Registered Office: Fifth Floor, Ibex House, 42-47 Minories, London EC3N 1DY. Breast Cancer Now has a Welsh office in Cardiff. Professor Matt Smalley, from Cardiff University’s European Cancer Stem Cell Research Institute, said: “There are 150 new cases of breast cancer diagnosed in the UK every day. Becoming Breast Cancer Now Support for you. Registered charity no. Breast Cancer Now works hard to provide the best information and support for people affected by breast cancer, wherever in the UK they may be. Please check back for updates. Stay in touch. Registered Office: Fifth Floor, Ibex House, 42-47 Minories, London EC3N 1DY. Potential new treatment for advanced cancers, European Cancer Stem Cell Research Institute, New insight into aggressive breast cancers. We can now build on this and can start to think about developing targeted therapies. Registered charity number 1113068 “We looked at a protein called LYN, which is involved in keeping cells alive and allowing them to divide, and found that it was no longer properly controlled in aggressive breast cancer cells and could drive the cancer cell growth, spread and invasion.” The team also found that in a subset of triple negative breast cancer cells associated with the BRCA1 gene mutation, LYN could be switched on and increase cancer cell survival directly as a result of the loss of BRCA1. A potential treatment for therapy-resistant breast cancer patients has been uncovered by researchers at Cardiff University. Been uncovered by researchers at Cardiff University everyone gets the support they need, European cancer Stem Cell research,. By breast cancer love to keep in touch about news, events and how you can help by! Events in Wales throughout the year, from Monday 6 April the majority of our undergraduates enter employment further. 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