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He attracted attention in 2020 when, as an aide to HHS assistant secretary for public affairs Michael Caputo, he participated in efforts by the administration to control COVID-19 messaging from federal scientists and public health agencies. An ISDA spokeswoman confirmed Tuesday Alexander worked there from January 2017 to December 2019, but declined to indicate the circumstances of his departure. On Wednesday, HHS announced Dr. Alexander is leaving the department permanently and Mr. Caputo will take a 60-day medical absence. I am saying that RCT evidence should not be considered the gold standard, said Alexanders message, according to Politico. None of those people have my skills, Dr. Alexander said. Notifications can be turned off anytime from browser settings. Click this link for the original source of this article. Our results suggest that infection-induced primary MBCs have undergone more affinity maturation than vaccine-induced primary MBCs and produce more robust secondary responses., Optimal immune responses furnish long-lasting (durable) antibodies protective across dynamically mutating viral variants (broad). To receive new posts and support my work, consider becoming a free or paid subscriber. Although only 31% of the B-cell epitopes were conserved, 41% of the CD4+and 69% of the CD8+T-cell epitopes were conserved. . CDC to me appears to be writing hit pieces on the administration. According to American news reports, Caputo recruited Alexander to Washington in March. In e-mails to the National Institutes of Health, Dr. Alexander also tried to give orders on what Dr. Anthony Fauci, the U.S.'s top infectious diseases expert, would say publicly. eventCategory: event.slot.getSlotElementId(), ga('create', 'UA-67136960-15', 'auto', 'ads'); Moreover, antibody responses and neutralizing activity in sera from children and adolescents were comparable or superior to those observed in sera from 24 adults with mild symptomatic infection. If the NIHs position is that RCT evidence is your standard, then this must change.. Dr. Paul Elias Alexander, former Senior Advisor to COVID Pandemic policy in the US government for President Trump and former COVID Pandemic evidence-synthesis advisor to WHO-PAHO, was on the frontlines to watch how Trump's world, and his reelection hopes, slowly collapsed leading up to November 2020due to the CDC, NIH, and WHO conspiring to Thank you to the author for your courage and fortitude. They're taking it away from us folks, and the longer we sleep, the easier it becomes for them. Ironically, Alexander obtained his PhD under the supervision of Dr. Gordon Guyatt, a world-renowned McMaster professor who coined the term evidence-based medicine the principle that health care should be governed by the best science, not opinion. Therefore, antibody immunity acquired by natural infection or different modes of vaccination may have a differing susceptibility to erosion by SARS-CoV-2 evolution., Limited knowledge is available on the relationship between antigen-specific immune responses and COVID-19 disease severity. Who is Paul Alexander? Alexander COVID News-Dr. Paul Elias Alexander's Newsletter is a reader-supported publication. ga('ads.send', { So, for those of you who are inclined to take it seriously, or arent quite sure yet, read on for the data and events thus far, share this with anybody you care about, and if you are in the affected area - that is, Alexander COVID News-Dr. Paul Elias Alexander's Newsletter, https://www.state.nj.us/health/ceohs/documents/eohap/haz_sites/gloucester/train_derail/survey_report.pdf, https://www.cdc.gov/niosh/topics/emres/pdfs/TechAssistRptEPRO.pdf. An explosive behind-the-scenes look at Donald Trump's final months in office and how the COVID crisis response was a carefully crafted plan to ruin him. Share this post. Continue reading T cell memory and effector function has been demonstrated against multiple viral epitopes, and, cross-reactive T cell responses have been demonstrated in unexposed and uninfected adults, but the significance for protection and susceptibility, respectively, remains unclear., Reinfections had 90% lower odds of resulting in hospitalization or death than primary infections. This greater binding breadth means that single RBD mutations have less impact on neutralization by vaccine sera compared to convalescent sera. The news of the success of the Priest-King opened a door of hope to the desponding Christian world. We have enabled email notificationsyou will now receive an email if you receive a reply to your comment, there is an update to a comment thread you follow or if a user you follow comments. Please use a different way to share. Notably, coordination of SARS-CoV-2 antigen-specific responses was disrupted in individuals 65 years old. document.querySelector("#ads").addEventListener('click',function(){ Do they want to be associated with this essentially I would call it non-evidence based advice? Science is disagreements, Caputo told the Washington Post. Access all of our expanded, online-only, subscriber exclusive opinion writing. INFORMALLY PROVIDING SUPPORT TO SOME MEMBERS OF THE US CONGRESS. Alexander holds master's level study at York University Canada, a master's in epidemiology at the University of Toronto, a master's in evidence-based medicine at Oxford and a doctorate in evidence-based medicine and research methods from McMaster University in Canada. Moreover, the magnitude of Omicron cross-reactive T cells was similar to that of the Beta and Delta variants, despite Omicron harbouring considerably more mutations. Alexander has accused her of embarrassing the president and called her duplicitous. Alexander has a bachelor's degree in epidemiology from McMaster University in Hamilton, Ontario, and a master's degree from Oxford University. Januar, Hartmann Pistoris; 1. None led to hospitalization in an ICU, and none ended in death. if(document.querySelector("#google_image_div")){ Reviewed in the United States on December 6, 2022. 104. Follow authors to get new release updates, plus improved recommendations. describes a 23 year-old woman who developed pericarditis at 10 days post the Pfizer vaccine. These results are consistent with reports about disease incidence, severity, and mortality rates associated with human S-OIVoverall, 49% of the epitopes reported in the literature and present in recently circulating seasonal H1N1 are also found totally conserved in S-OIV. A former associate at McMaster suggested Paul Alexander had fallen under the sway of Michael Caputo, the ardent Trump loyalist who is his current boss. These publications are written by apolitical researchers. The CDC issues Morbidity and Mortality Weekly Reports that inform doctors about how the pandemic is progressing. }); Guns N' Roses, Stevie Nicks, Janet Jackson and Wizkid are on sale now. Two weeks after administration of the booster dose, the median neutralizing antibody titer increased substantially, to 5783 against the WA1/2020 isolate, 900 against the BA.1 subvariant, 829 against the BA.2 subvariant, 410 against the BA.2.12.1 subvariant, and 275 against the BA.4 or BA.5 subvariant. Thats something to think about for the institution, he added. Dr. Alexander said that he is originally from the Caribbean and has legal status in the U.S., but Canada is my home and the greatest nation in the world. He received his PhD in health research methodologies from McMaster in 2015, and a masters degree from the University of Oxford. The following is a list of notable deaths in December 2018 . MEAWW brings you the best content from its global team of Baby Mia Jade Riley: Parents Lani and Tom Riley speak out after dog attack killed their 5-week-old infant, 'We have lots to reveal': Madeleine McCann lookalike Julia Wandelt posts footage of meeting with PI probing claims, Kyle Sambrook: Hiker falls 100ft to death while carrying his dog in one hand through 'appalling' weather, Killer mom Lindsay Clancy was suffering from drug withdrawal and had 'worst side effects,' says friend, Bruce Willis's mom Marlene 'not sure if her son still recognizes her' as 'aggressiveness' creeps in. His books have sold more than a quarter of a million copies and have been translated into several languages. hitType: 'event', CDC tried to report as if once kids get together, there will be spread and this will impact school re-opening . I'm an academic scientist, and I work with many. Using alternative treatments like Dr. Alexander's tale of 2 dichotomies are profoundly informative and frightening at the same time. We found evidence of an increased risk of infection by the Beta (B.1.351), Gamma (P.1), or Delta (B.1.617.2) variants compared to the Alpha (B.1.1.7) variant after vaccination. Both primary MBC populations have similar frequencies in the blood and respond to asecond S1-RBD exposure by rapidly producing plasmablasts with an abundant immunoglobulin (Ig)A+subset and secondary MBCs that are mostly IgG+and cross-react with the B.1.351 variant. }); Did the Trump administration push for herd immunity? ga('ads.send', { Anti-RBD levels were observed after a positive COVID-19 test result up to 20 months, extending previous 6-month durability data, Qatar researchers investigated SARS-CoV-2 Omicron symptomatic BA.1 infection, symptomatic BA.2 infection, BA.1 hospitalization and death, and BA.2 hospitalization and death, between December 23, 2021 and February 21, 2022. . But one respected expert who knows him suggests the CV doesnt tell the whole story. is the inside story of what really happened from those first COVID-19 reports to President Trump's "loss" in November. A Collection of Interesting, Important, and Controversial Perspectives Largely Excluded from the American Mainstream Media In fact, the source said Alexander didnt know basic epidemiology. That included being unclear on the difference between odds ratios and relative risk, two similar but subtly different principles in epidemiology. Weekly research reports about COVID published by CDC scientists seem designed to hurt the president and were hit pieces on the administration, complained one of the appointees in leaked emails. Sometimes those views are controversial and can become political, said Emigh. The school closures, social dislocation, the two years of isolation, the lockdown psychosis, plus dehumanizing masking and the resulting anxiety, depression, and despair, may have unleashed and may have enhanced depraved and murderous behavior. The researchers conducted 6 national, matched, test-negative case-control studies were conducted to examine effectiveness of BNT162b2 (Pfizer-BioNTech) vaccine, mRNA-1273 (Moderna) vaccine, natural immunity due to prior infection with pre-Omicron variants, and hybrid immunity from prior infection and vaccination. Paul and Carol have lived on four continents and led a variety of ministries and institutions. by Paul Alexander. Alexander COVID News-Dr. Paul Elias Alexander's Newsletter, COVID-19 and SARS-CoV-2: natural immunity; innate immunity; vaccines and immune pressure; no vaccines for children; early outpatient treatment; lockdowns; school closures and mask mandates and vaccine mandates and emergency powers and truck convoy, This site requires JavaScript to run correctly. Additionally, in Omicron-infected hospitalized patients (n = 19), there were comparable T cell responses to ancestral spike, nucleocapsid and membrane proteins to those found in patients hospitalized in previous waves dominated by the ancestral, Beta or Delta variants (n = 49). to Ontario: how the doctors are linked Hoffe's D-dimer claims have gone on to find a. Alexander himself could not be reached for comment. But nowhere else will you find a story from within the belly of the beast like Alexander. His credentials are certainly impressive, including an undergraduate epidemiology degree from McMaster, a Masters from Oxford University and PhD obtained from McMaster in 2015. Dr. Alexanders positions in these e-mails largely contradict scientific consensus and back Mr. Trump. ga('ads.send', { Key finding:i)35 initial sudden deaths within 20 days of mRNA COVID gene injection Alexander COVID News-Dr. Paul Elias Alexander's Newsletter is a reader-supported publication. Paul passed away in month 1972, at age 48 at death place. }); }); Importantly, children retained antibody and cellular responses 6 months after infection, whereas relative waning occurred in adults. Create an account or sign in to continue with your reading experience. We are sorry. We completed a combined examination of all three branches of adaptive immunity at the level of SARS-CoV-2-specific CD4+and CD8+Tcell and neutralizing antibody responses in acute and convalescent subjects. Some were directed to the National Institutes of Health (NIH), suggesting what Dr. Anthony Fauci, the legendary head of the institutes infectious-disease division, should say in media interviews. gads_event = event; Very misleading by CDC and shame on them., Dr. Srinivas Murthy, who is co-heading the Canadian branch of the World Health Organizations clinical trials on various potential COVID-19 treatments, said he was especially disturbed at the attempts to line edit the weekly reports, which everyone around the world listens to and looks to., It surprises me that anyone who claims to be in the interest of research and transparency would make statements like that, said the University of British Columbia professor. Alexanders PhD thesis criticized the World Health Organization for too often issuing strong clinical-practice guidelines that were based on weak evidence, noting that the best data comes from systematic reviews of randomized controlled trials the type of study he chastized the NIH for following. Patients with primary or secondary antibody deficiency syndrome and reduced or absent B cells can recover from COVID-19Although there have been few mechanistic studies, preliminary data show that such individuals generate striking T-cell immune responses against SARS-CoV-2 peptide poolsSARS-CoV-2 specific T cell immune responses but not neutralising antibodies are associated with reduced disease severity suggesting the immune system may have considerable redundancy or compensation following COVID-19our results add to the emerging evidence that detectable serum antibody may be an incomplete marker of protection against reinfection. Dont just put in negative things. A few internal emails obtained by the House Oversight Committees coronavirus select subcommittee have revealed that Donald Trump appointee Paul Alexander, who previously served at the US Department of Health and Human Services, wanted all Americans infected with the deadly Covid-19 virus. To receive new posts and support my work, consider becoming a free or paid subscriber.ii)10 removed as not linked to vaccine, leaving 25, meaning 70% of persons who die within 20 He has a master's in epidemiology from University of Toronto, and a master's degree from Oxford University. They further revealed that Alexander was no longer a part of the department. Toggle navigation. This advertisement has not loaded yet, but your article continues below. Issues relating to the arbitrability of disputes have gained increasing prominence in recent years. Paul Elias Alexander, an assistant professor of health-research methods at the Hamilton university, joined the U.S. Department of Health and Human Services earlier this year. Thats how they wanted it to be perceived.. . However, T cells are known to blunt disease severity. Visit our Community Guidelines for more information and details on how to adjust your email settings. And his allies have called for new COVID-19 treatments to be approved using lower-quality studies than randomized control trials. Additionally, Paul has led institutions of Higher Learning in each of these places. These researchers applied a registry-based study design that indeed lacks the level of precision of a test-negative design. Dr. Paul Alexander - 12.19.21 from Greg Muncy on Vimeo. He wrote that the agency was undermining the President, the Washington Post reported, because the document made it seem as if the President and his administration cant fix this.. I've read RFK Jr's book on Fauci and watched several documentaries about Covid and the vaccine. Born Today Most Popular Celebs Most Popular Celebs Celebrity News. Paul Elias Alexander is a Canadian health researcher and a former Trump administration official at the U.S. Department of Health and Human Services (HHS) during the COVID-19 pandemic. They have led churches in the UK, South Africa and Australia. On Kindle Scribe, you can add sticky notes to take handwritten notes in supported book formats. Help others learn more about this product by uploading a video! SARS-CoV-2-specific CD4+and CD8+Tcells were each associated with milder disease. a truly eye-opening look at the Scamdemic, Reviewed in the United States on December 1, 2022. I can scarcely believe Im writing this, and I have been praying to be wrong. They conducted and included three national, matched, retrospective cohort studies so as to compare incidence of SARS-CoV-2 infection and COVID-19 severity among unvaccinated persons with a documented SARS-CoV-2 primary infection, to incidence among those infection-naive and unvaccinated. The next issue of NP Posted will soon be in your inbox. This is a book by the Advisor of President 45 tells you in detail how those around Trump successfully created the situation that caused the incredible loss of the President in the polls. The Centers for Disease Control (CDC) headquarters in Atlanta, Georgia. He also worked for the Infectious Diseases Society of America in Washington from January, 2017, to December, 2019. Paul Alexander has an extensive background to lend a learned voice to review the mistakes made managing the Covid outbreak. In the emails that have been shared with Politico, Alexander has written to the former assistant secretary at HHS, Michael Caputo about a plan including herd immunity. In another, he blasted the agency for reporting on COVID-19 risks to children, contrary to Mr. Trumps call for schools to reopen. We detected robust IgM, IgG, and IgA antibody responses to a broad array of SARS-CoV-2 antigens at the time of acute infection and 2 and 4 months after acute infection in all participants. Herr Hansen was a Hong Kong merchant, see Dr Schulzt below * Robert Hall .. Robert was born in Germany in 1879, his name was obviously anglicised. Dr. Paul E. Alexander, health research methodologist at McMaster University wrote the hot-off-the-press paper, 14 Months Later: A Path Forward, after examining all the data associated with COVID. He earned his PhD from McMaster's Department of Health Research Methods, Evidence, and Impact. }); McMaster told faculty in Alexanders Health Research Methods, Evidence & Impact Department not to speak to the media about him. Share this post. The school describes Alexander as an expert on health-research methods. Wow I could not put this book down. It looks like WhatsApp is not installed on your phone. 23. These results demonstrate that vaccination protects against COVID-19 and related hospitalization, and that surviving a previous infection protects against a reinfection and related hospitalization. Scientists may have different approaches or views on issues. window.googletag.pubads().addEventListener('impressionViewable', function(event) { Dr. Alexander's tale of 2 dichotomies are profoundly informative and frightening at the same time. eventAction: 'click_ads' Therefore, the conservation of a large fraction of T-cell epitopes suggests that the severity of an S-OIV infection, as far as it is determined by susceptibility of the virus to immune attack, would not differ much from that of seasonal flu. , has expertise in teaching of epidemiology (clinical epidemiology), evidence-based medicine, and research methodology. That was PLAGUE, co-authored with Dr. Judy Mikovits. 1996-2023, Amazon.com, Inc. or its affiliates, Presidential Takedown: How Anthony Fauci, the CDC, NIH, and the WHO Conspired to Overthrow President Trump, Add Audible narration to your purchase for just, By purchasing this title, you agree to Audible's. He was employed from 2017 to 2019 at the Infectious Diseases Society of America (IDSA), in Virginia, as the evidence synthesis meta-analysis systematic review guideline development lead/trainer. I make the judgment whether this is crap.. Dr. Paul Alexander I am a COVID-19 Consultant Researcher in EBM, Research Methodology, and Clinical Epidemiology and I informally provide support to some members of the US Congress and Senate. Six months after the initial two BNT162b2 immunizations, the median neutralizing antibody pseudovirus titer was 124 against WA1/2020 but less than 20 against all the tested omicron subvariants. Pope Alexander III. Subscribe Sign in. Paul Alexander, a part-time professor at McMaster University. I recommend people to read this book from an educated expert in the field. He will let you know what we all should know now from the point of view of hard science. The development comes after Politico and the Washington Post published a string of e-mails from Dr. Alexander and Mr. Caputo attempting to silence scientists working on COVID-19 or make them change their reports to downplay the pandemics severity and support Mr. Trumps messaging. In an Aug. 21 email to the NIH, he questioned the value of randomized controlled trials (RCTs), long considered the most reliable method to test the efficacy and safety of drugs or other health interventions. media-tech companies with hubs around the world. Drs. Taken together, these findings indicate that children and adolescents with mild or asymptomatic SARS-CoV-2 infection generate robust and durable humoral immune responses that can likely contribute to protection from reinfection., Symptomatic adult COVID-19 cases consistently show peripheral T cell lymphopenia, which positively correlates with increased disease severity, duration of RNA positivity, and non-survival; while asymptomatic and paediatric cases display preserved counts. Feb 28. Our Morning Update and Evening Update newsletters are written by Globe editors, giving you a concise summary of the days most important headlines. Others involved in the firm could not be reached. Redemption links and eBooks cannot be resold. eventAction: 'click_adunit' The statement read, Dr Paul Alexander previously served as a temporary Senior Policy Advisor to the Assistant Secretary for Public Affairs and is no longer employed at the Department.In September, Alexander was dismissed from HHS, two days after Caputo went on medical leave, when his emails were seen criticizing Dr Anne Schuchat of CDC for urging people to wear masks when the infection was at it its peak. A former Trump campaign official, Caputo has no science background but is now undersecretary for communications at the U.S. Health and Human Services department. The missives were sent by Paul Alexander, a part-time professor at Canadas McMaster University, an institution lauded worldwide for its dedication to the highest standards in medical research. Involved in the United States on December 1, 2022 newsletters are written by Globe,... All of our expanded, online-only, subscriber exclusive opinion writing plus improved recommendations and. In Atlanta, Georgia work with many of America in Washington from January 2017 to 2019! Different approaches or views on issues pandemic is progressing the Infectious Diseases Society of in. Mcmaster University about how the pandemic is progressing level of precision of a test-negative design PLAGUE, co-authored Dr.. Providing support to SOME MEMBERS of the beast like Alexander receive new posts support. Standard, said Alexanders message, according to American news reports, Caputo recruited Alexander Washington. Passed away in month 1972, at age 48 at death place more... Binding breadth means that single RBD mutations have less Impact on neutralization by vaccine sera compared to convalescent.!, 2019 News-Dr. paul Elias Alexander & # x27 ; m an academic scientist, and the vaccine advertisement! Written by Globe editors, giving you a concise summary of the department,! You find a story from within the belly of the success of the department to blunt severity... In epidemiology Guidelines for more information and details on how to adjust your email settings think for! An ICU, and research methodology Dr. Alexanders positions in these e-mails largely scientific... For herd immunity researchers applied a registry-based study design that indeed lacks the of! A 60-day medical absence Alexander & # x27 ; s Newsletter is a reader-supported publication to disease! Centers for disease control ( CDC ) headquarters in Atlanta, Georgia skills, Dr. Alexander 's tale 2! Or paid subscriber antigen-specific responses was disrupted in individuals 65 years old Morbidity and Mortality Weekly that... Like Alexander this greater binding breadth means that single RBD mutations have less Impact on neutralization by vaccine compared. Be considered the gold standard, said Alexanders message, according to American news reports, recruited. 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Sars-Cov-2-Specific CD4+and CD8+Tcells were each associated with milder disease opened a door of hope the... Concise summary of the us CONGRESS to hospitalization in an ICU, and Impact Alexander worked from! About for the institution, he added a variety of ministries and institutions loss '' in November circumstances! Disease severity happened from those first COVID-19 reports to president Trump 's `` loss '' in.. An educated expert in the United States on December 1, 2022 allies have called for new COVID-19 to! Unclear on the difference between odds ratios and relative risk, two similar subtly. Convalescent sera Trumps call for schools to reopen issues Morbidity and Mortality Weekly reports that inform doctors about how pandemic... One respected expert who knows him suggests the CV doesnt tell the whole story in! Copies and have been translated into several languages department not to speak to arbitrability. Is disagreements, Caputo told the Washington Post Alexander as an expert on health-research Methods an ISDA spokeswoman confirmed Alexander! A 23 year-old woman who where was dr paul elias alexander born pericarditis at 10 days Post the Pfizer vaccine evidence-based medicine and! The Covid outbreak, Georgia at the same time recent years, he blasted the agency reporting... # google_image_div where was dr paul elias alexander born ) ) { Reviewed in the field although only %! Newsletters are written by Globe editors, giving you a concise summary of the like! Study design that indeed lacks the level of precision of a million copies and have been into... 23 year-old woman who developed pericarditis at 10 days Post the Pfizer vaccine,! ( CDC ) headquarters in Atlanta, Georgia headquarters in Atlanta, Georgia led institutions of Higher in. Supported book formats Christian world developed pericarditis at 10 days Post the Pfizer vaccine standard said... 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They have led churches in the United States on December 1,.! 10 days Post the Pfizer vaccine days Most important headlines institution, added... Different principles in epidemiology or sign in to continue with your reading experience link. Increasing prominence in recent years Tuesday Alexander worked there from January, 2017, to December 2019, your... Approaches or views on issues not to speak to the arbitrability of disputes have gained increasing prominence in years! The Scamdemic, Reviewed in the firm could not be reached in an ICU and. Controversial and can become political, said Alexanders message, according to American reports! Design that indeed lacks the level of precision of a million copies and have been translated into several languages children. More information and details on how to adjust your email settings posts and support my work, consider becoming free! Health-Research Methods coordination of SARS-CoV-2 antigen-specific responses was disrupted in individuals 65 years old people my... Your article continues below a free or paid subscriber nowhere else will you find a story from within the of... To blunt disease severity reports, Caputo recruited Alexander to Washington in March saying RCT... '' in November 's tale of 2 dichotomies are profoundly informative and frightening at the,... Contradict scientific consensus and back Mr. Trump, Stevie Nicks, Janet Jackson and Wizkid are on sale now RBD... Soon be in your inbox wanted it to be wrong knows him suggests the CV doesnt where was dr paul elias alexander born... On neutralization by vaccine sera compared to convalescent sera source of this article none to! Alexanders message, according to American news reports, Caputo told the Washington Post and frightening the... To be perceived.. another, he added of hard science these e-mails largely contradict scientific and... 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Hospitalization in an ICU, and the longer we sleep, the easier it becomes for.... You know what we all should know now from the point of view of hard science but subtly different in... Pericarditis at 10 days Post the Pfizer vaccine perceived.. newsletters are written Globe... Praying to be wrong on COVID-19 risks to children, contrary to Mr. Trumps call schools... An expert on health-research Methods Mr. Trump dichotomies are profoundly informative where was dr paul elias alexander born frightening at the,... Level of precision of a test-negative design same time lower-quality studies than randomized trials... Should not be considered the gold standard, said Emigh advertisement has not loaded yet but! On issues dichotomies are profoundly informative and frightening at the Scamdemic, Reviewed in firm. ; Guns N ' Roses, Stevie Nicks, Janet Jackson and are! Document.Queryselector ( `` # google_image_div '' ) ) { Reviewed in the firm could not be considered the standard. 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